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Specificity in PDZ-peptide interaction networks: Computational analysis and review
Globular PDZ domains typically serve as protein–protein interaction modules that regulate a wide variety of cellular functions via recognition of short linear motifs (SLiMs). Often, PDZ mediated-interactions are essential components of macromolecular complexes, and disruption affects the entire scaf...
Autores principales: | Amacher, Jeanine F., Brooks, Lionel, Hampton, Thomas H., Madden, Dean R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138185/ https://www.ncbi.nlm.nih.gov/pubmed/32289118 http://dx.doi.org/10.1016/j.yjsbx.2020.100022 |
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