A novel CX3CR1 inhibitor AZD8797 facilitates early recovery of rat acute spinal cord injury by inhibiting inflammation and apoptosis

The present study aimed to evaluate the effect of the CX3CR1 inhibitor AZD8797 in early recovery after acute SCI and elucidate its potential mechanism in blocking inflammation and apoptosis. Adult rats were sacrificed after 3, 7, 10, or 14 days of SCI. The injured spinal tissues were collected for a...

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Detalles Bibliográficos
Autores principales: Chen, Guozhao, Zhou, Zhiping, Sha, Weiping, Wang, Liming, Yan, Fei, Yang, Xiaomei, Qin, Xia, Wu, Muyao, Li, Di, Tian, Shoujin, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138267/
https://www.ncbi.nlm.nih.gov/pubmed/32323731
http://dx.doi.org/10.3892/ijmm.2020.4509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138267/
https://www.ncbi.nlm.nih.gov/pubmed/32323731
http://dx.doi.org/10.3892/ijmm.2020.4509

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