Cargando…

Development of an ex vivo xenogeneic bone environment producing human platelet-like cells

The efficiency of in vitro platelet production is considerably low compared with physiological activity due to the lack of pivotal factors that are essential in vivo. We developed an ex vivo platelet production system, introducing human megakaryocytes into an isolated porcine thighbone and culturing...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujiyama, Shingo, Hori, Nobuyasu, Sato, Toshiyuki, Enosawa, Shin, Murata, Mitsuru, Kobayashi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138292/
https://www.ncbi.nlm.nih.gov/pubmed/32255777
http://dx.doi.org/10.1371/journal.pone.0230507