A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers

Ataxia-telangiectasia mutated (ATM) is an apical kinase of the DNA damage response following DNA double-strand breaks (DSBs); however, the mechanisms of ATM activation are not completely understood. Long noncoding RNAs (lncRNAs) are a class of regulatory molecules whose significant roles in DNA dama...

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Detalles Bibliográficos
Autores principales: Zhao, Kunming, Wang, Xingwen, Xue, Xuting, Li, Li, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138317/
https://www.ncbi.nlm.nih.gov/pubmed/32203529
http://dx.doi.org/10.1371/journal.pbio.3000666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138317/
https://www.ncbi.nlm.nih.gov/pubmed/32203529
http://dx.doi.org/10.1371/journal.pbio.3000666

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