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Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis

The role of proteins often changes during evolution, but we do not know how cells adapt when a protein is asked to participate in a different biological function. We forced the budding yeast, Saccharomyces cerevisiae, to use the meiosis-specific kleisin, recombination 8 (Rec8), during the mitotic ce...

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Detalles Bibliográficos
Autores principales: Hsieh, Yu-Ying Phoebe, Makrantoni, Vasso, Robertson, Daniel, Marston, Adèle L., Murray, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138332/
https://www.ncbi.nlm.nih.gov/pubmed/32155147
http://dx.doi.org/10.1371/journal.pbio.3000635