Mislocalized cytoplasmic p27 activates PAK1‐mediated metastasis and is a prognostic factor in osteosarcoma

The development of pulmonary metastasis is the leading cause of death in osteosarcoma (OS), which is the most common malignant bone tumor in children. We have previously reported that the tumor suppressor p27 (KIP1, CDKN1B) is frequently mislocalized to the cytoplasm of OS. However, its prognostic s...

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Detalles Bibliográficos
Autores principales: Chen, Xiang, Cates, Justin M. M., Du, Yu-Chen, Jain, Antrix, Jung, Sung Yun, Li, Xiao-Nan, Hicks, John M., Man, Tsz‐Kwong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138393/
https://www.ncbi.nlm.nih.gov/pubmed/31872963
http://dx.doi.org/10.1002/1878-0261.12624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138393/
https://www.ncbi.nlm.nih.gov/pubmed/31872963
http://dx.doi.org/10.1002/1878-0261.12624

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