Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells

Platinum‐based compounds remain a well‐established chemotherapy for cancer treatment despite their adverse effects which substantially restrict the therapeutic windows of the drugs. Both the cell type‐specific toxicity and the clinical responsiveness of tumors have been associated with mechanisms th...

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Detalles Bibliográficos
Autores principales: Melnikova, Margarita, Wauer, Ulrike Sophie, Mendus, Diana, Hilger, Ralf Axel, Oliver, Trudy G., Mercer, Kim, Gohlke, Björn Oliver, Erdmann, Kati, Niederacher, Dieter, Neubauer, Hans, Buderath, Paul, Wimberger, Pauline, Kuhlmann, Jan Dominik, Thomale, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138396/
https://www.ncbi.nlm.nih.gov/pubmed/32037720
http://dx.doi.org/10.1002/1878-0261.12648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138396/
https://www.ncbi.nlm.nih.gov/pubmed/32037720
http://dx.doi.org/10.1002/1878-0261.12648

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