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Rapid stromal remodeling by short‐term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma

Anti‐angiogenic agents combined with chemotherapy is an important strategy for the treatment of solid tumors. However, survival benefit is limited, urging the improvement of combination therapies. We aimed to clarify the effects of vascular endothelial growth factor receptor 2 (VEGFR2) targeting on...

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Detalles Bibliográficos
Autores principales: Steins, Anne, Klaassen, Remy, Jacobs, Igor, Schabel, Matthias C., van Lier, Monique G. J. T. B., Ebbing, Eva A., Hectors, Stefanie J., Tas, Sander W., Maracle, Chrissta X., Punt, Cornelis J. A., Siebes, Maria, Bergman, Jacques J. G. H. M., Medema, Jan Paul, Wilmink, Johanna W., Mathot, Ron A. A., Strijkers, Gustav J., Bijlsma, Maarten F., van Laarhoven, Hanneke W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138404/
https://www.ncbi.nlm.nih.gov/pubmed/31733011
http://dx.doi.org/10.1002/1878-0261.12599