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Prolyl 4‐hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas, and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls

Melanoma is an unpredictable, highly metastatic malignancy, and treatment of advanced melanoma remains challenging. Novel molecular markers based on the alterations in gene expression and the molecular pathways activated or deactivated during melanoma progression are needed for predicting the course...

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Detalles Bibliográficos
Autores principales: Eriksson, Johanna, Le Joncour, Vadim, Jahkola, Tiina, Juteau, Susanna, Laakkonen, Pirjo, Saksela, Olli, Hölttä, Erkki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138405/
https://www.ncbi.nlm.nih.gov/pubmed/32053263
http://dx.doi.org/10.1002/1878-0261.12649