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SMAD3/SP1 complex‐mediated constitutive active loop between lncRNA PCAT7 and TGF‐β signaling promotes prostate cancer bone metastasis

Bone metastasis is associated with cancer‐related death in patients with prostate cancer (PCa). Long noncoding RNAs (lncRNAs) play critical roles in tumor progression of PCa. Nevertheless, the biological function of lncRNAs in PCa bone metastasis remains unclear. PCAT7 was identified as a bone metas...

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Detalles Bibliográficos
Autores principales: Lang, Chuandong, Dai, Yuhu, Wu, Zhengquan, Yang, Qing, He, Shaofu, Zhang, Xin, Guo, Wei, Lai, Yingrong, Du, Hong, Wang, Hehe, Ren, Dong, Peng, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138406/
https://www.ncbi.nlm.nih.gov/pubmed/31925912
http://dx.doi.org/10.1002/1878-0261.12634