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A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging

Photobleaching limits extended imaging of fluorescent biological samples. Here, we developed DNA based “FluoroCubes” that are similar in size to the green fluorescent protein (GFP), have single-point attachment to proteins, have a ~54-fold higher photobleaching lifetime and emit ~43-fold more photon...

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Detalles Bibliográficos
Autores principales: Niekamp, Stefan, Stuurman, Nico, Vale, Ronald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138518/
https://www.ncbi.nlm.nih.gov/pubmed/32203385
http://dx.doi.org/10.1038/s41592-020-0782-3