Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins

Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed. Single-domain antibodies (VHH) have been examined as a countermeasure for BoNT because of their high stability and ease of production. Here, we inve...

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Detalles Bibliográficos
Autores principales: Lam, Kwok-ho, Tremblay, Jacqueline M., Vazquez-Cintron, Edwin, Perry, Kay, Ondeck, Celinia, Webb, Robert P., McNutt, Patrick M., Shoemaker, Charles B., Jin, Rongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138525/
https://www.ncbi.nlm.nih.gov/pubmed/32101733
http://dx.doi.org/10.1016/j.celrep.2020.01.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138525/
https://www.ncbi.nlm.nih.gov/pubmed/32101733
http://dx.doi.org/10.1016/j.celrep.2020.01.107

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