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Metformin coordinates osteoblast/osteoclast differentiation associated with ischemic osteonecrosis

In this study, we aimed to identify a candidate drug that can activate endogenous Angiopoietin 1 (Ang1) expression via drug repositioning as a pharmacological treatment for avascular osteonecrosis. After incubation with 821 drugs from the Food and Drug Administration (FDA)-approved drug library, Ang...

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Detalles Bibliográficos
Autores principales: Park, See-Hyoung, Kang, Mi-Ae, Moon, Young Jae, Jang, Kyu Yun, Kim, Jung Ryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138543/
https://www.ncbi.nlm.nih.gov/pubmed/32045366
http://dx.doi.org/10.18632/aging.102796