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MicroRNA-325-3p prevents sevoflurane-induced learning and memory impairment by inhibiting Nupr1 and C/EBPβ/IGFBP5 signaling in rats

Endoplasmic reticulum stress-induced neuronal apoptosis contributes to neurotoxicity observed after sevoflurane exposure. However, the molecular mechanism underlying the resulting learning and memory impairments remains unknown. Here, we investigated the roles of miR-325-3p and Nupr1 in sevoflurane-...

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Detalles Bibliográficos
Autores principales: Xu, Lili, Xu, Qi, Xu, Fang, Zhang, Wenxin, Chen, Qing, Wu, Hui, Chen, Xinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138556/
https://www.ncbi.nlm.nih.gov/pubmed/32191629
http://dx.doi.org/10.18632/aging.102942