Intranasal delivery of 9-cis retinoic acid reduces beta-amyloid deposition via inhibiting astrocyte-mediated inflammation

Alzheimer's disease (AD) is associated with the accumulation and deposition of a beta-amyloid (Αβ) peptide in the brain, resulting in increased neuroinflammation and synaptic dysfunction. Intranasal delivery of targeted drugs to the brain represents a noninvasive pathway that bypasses the blood...

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Detalles Bibliográficos
Autores principales: Zhao, Hong, Li, Shuo, Li, Zhuo, Yang, Shuo, Li, Dandan, Zheng, Jiaolin, Gao, Hongmei, Yun, Ling, Gu, YingLi, Li, Longxuan, Zhao, Jing, Fu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138573/
https://www.ncbi.nlm.nih.gov/pubmed/32209731
http://dx.doi.org/10.18632/aging.102970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138573/
https://www.ncbi.nlm.nih.gov/pubmed/32209731
http://dx.doi.org/10.18632/aging.102970

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