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Intranasal delivery of 9-cis retinoic acid reduces beta-amyloid deposition via inhibiting astrocyte-mediated inflammation

Alzheimer's disease (AD) is associated with the accumulation and deposition of a beta-amyloid (Αβ) peptide in the brain, resulting in increased neuroinflammation and synaptic dysfunction. Intranasal delivery of targeted drugs to the brain represents a noninvasive pathway that bypasses the blood...

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Detalles Bibliográficos
Autores principales:	Zhao, Hong, Li, Shuo, Li, Zhuo, Yang, Shuo, Li, Dandan, Zheng, Jiaolin, Gao, Hongmei, Yun, Ling, Gu, YingLi, Li, Longxuan, Zhao, Jing, Fu, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138573/ https://www.ncbi.nlm.nih.gov/pubmed/32209731 http://dx.doi.org/10.18632/aging.102970

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