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Integrative analysis of DNA methylation and gene expression reveals distinct hepatocellular carcinoma subtypes with therapeutic implications

We aimed to develop an HCC classification model based on the integrated gene expression and methylation data of methylation-driven genes. Genome, methylome, transcriptome, proteomics and clinical data of 369 HCC patients from The Cancer Genome Atlas Network were retrieved and analyzed. Consensus clu...

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Detalles Bibliográficos
Autores principales: Huang, Xiaowen, Yang, Chen, Wang, Jilin, Sun, Tiantian, Xiong, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138576/
https://www.ncbi.nlm.nih.gov/pubmed/32201399
http://dx.doi.org/10.18632/aging.102923