Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis

Interleukin 18 (IL-18) promotes inflammation and apoptosis in chondrocytes, thereby contributing to the development and progression of osteoarthritis (OA). Here, we investigated the effects of IL-18 treatment and inhibition in rat chondrocytes in vitro and in vivo. We used RT-PCR and Western blottin...

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Detalles Bibliográficos
Autores principales: Bao, Jiapeng, Chen, Zhonggai, Xu, Langhai, Wu, Lidong, Xiong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138594/
https://www.ncbi.nlm.nih.gov/pubmed/32182210
http://dx.doi.org/10.18632/aging.102937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138594/
https://www.ncbi.nlm.nih.gov/pubmed/32182210
http://dx.doi.org/10.18632/aging.102937

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