β(3)-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes

Cardiomyocyte β(3)-adrenoceptors (β(3)-ARs) coupled to soluble guanylyl cyclase (sGC)-dependent production of the second messenger 3’,5’-cyclic guanosine monophosphate (cGMP) have been shown to protect from heart failure. However, the exact localization of these receptors to fine membrane structures...

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Detalles Bibliográficos
Autores principales: Schobesberger, Sophie, Wright, Peter T, Poulet, Claire, Sanchez Alonso Mardones, Jose L, Mansfield, Catherine, Friebe, Andreas, Harding, Sian E, Balligand, Jean-Luc, Nikolaev, Viacheslav O, Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138611/
https://www.ncbi.nlm.nih.gov/pubmed/32228862
http://dx.doi.org/10.7554/eLife.52221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138611/
https://www.ncbi.nlm.nih.gov/pubmed/32228862
http://dx.doi.org/10.7554/eLife.52221

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