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One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents

BACKGROUND: Thiazole and thiosemicarbazone derivatives are known to have potential anticancer activity with a mechanism of action related to inhibition of matrix metallo-proteinases, kinases and anti-apoptotic BCL2 family proteins. MATERIALS AND METHODS: A novel three series of 5-(1-(2-(thiazol-2-yl...

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Detalles Bibliográficos
Autores principales: Sayed, Abdelwahed R, Gomha, Sobhi M, Taher, Eman A, Muhammad, Zeinab A, El-Seedi, Hesham R, Gaber, Hatem M, Ahmed, Mahgoub M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138620/
https://www.ncbi.nlm.nih.gov/pubmed/32308369
http://dx.doi.org/10.2147/DDDT.S221263