Substitution of Dietary Sulfur Amino Acids by dl-2-Hydroxy-4-Methylthiobutyric Acid Reduces Fractional Glutathione Synthesis in Weaned Piglets

BACKGROUND: Cys is limiting for reduced glutathione (GSH) synthesis and can be synthesized from Met. We hypothesized that the dietary Met hydroxyl analogue dl-2-hydroxy-4-methylthiobutyric acid (dl-HMTBA) affects Cys and GSH metabolism and oxidative stress defense differently than Met. OBJECTIVE: Th...

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Detalles Bibliográficos
Autores principales: Rasch, Ilka, Görs, Solvig, Tuchscherer, Armin, Viergutz, Torsten, Metges, Cornelia C, Kuhla, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138682/
https://www.ncbi.nlm.nih.gov/pubmed/31773161
http://dx.doi.org/10.1093/jn/nxz272