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Irradiance, Photofrin(®) Dose and Initial Tumor Volume are Key Predictors of Response to Interstitial Photodynamic Therapy of Locally Advanced Cancers in Translational Models

The objective of the present study was to develop a predictive model for Photofrin(®)‐mediated interstitial photodynamic therapy (I‐PDT) of locally advanced tumors. Our finite element method was used to simulate 630‐nm intratumoral irradiance and fluence for C3H mice and New Zealand White rabbits be...

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Detalles Bibliográficos
Autores principales: Oakley, Emily, Bellnier, David, Hutson, Alan, Cooper, Hannah, Habitzruther, Michael, Sexton, Sandra, Curtin, Leslie, Tworek, Lawrence, Mallory, Matthew, Henderson, Barbara, Shafirstein, Gal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138700/
https://www.ncbi.nlm.nih.gov/pubmed/31887227
http://dx.doi.org/10.1111/php.13207