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Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha

As approximately 70% of human breast tumors are estrogen receptor α (ERα)-positive, estrogen and ERα play essential roles in breast cancer development. By interrupting the ERα signaling pathway, endocrine therapy has been proven to be an effective therapeutic strategy. In this study, we identified a...

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Detalles Bibliográficos
Autores principales: Gao, Yujing, Chen, Lijia, Han, Yali, Wu, Fangrui, Yang, Wen-Si, Zhang, Zheng, Huo, Tong, Zhu, Yingmin, Yu, Chengtai, Kim, Hong, Lee, Mark, Tang, Zhen, Phillips, Kevin, He, Bin, Jung, Sung Yun, Song, Yongcheng, Zhu, Bokai, Xu, Rui-Ming, Feng, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138820/
https://www.ncbi.nlm.nih.gov/pubmed/32265480
http://dx.doi.org/10.1038/s42003-020-0898-0