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Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins

Class I glutaredoxins are enzymatically active, glutathione-dependent oxidoreductases, whilst class II glutaredoxins are typically enzymatically inactive, Fe-S cluster-binding proteins. Enzymatically active glutaredoxins harbor both a glutathione-scaffold site for reacting with glutathionylated disu...

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Detalles Bibliográficos
Autores principales: Liedgens, Linda, Zimmermann, Jannik, Wäschenbach, Lucas, Geissel, Fabian, Laporte, Hugo, Gohlke, Holger, Morgan, Bruce, Deponte, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138851/
https://www.ncbi.nlm.nih.gov/pubmed/32265442
http://dx.doi.org/10.1038/s41467-020-15441-3