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Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins
Class I glutaredoxins are enzymatically active, glutathione-dependent oxidoreductases, whilst class II glutaredoxins are typically enzymatically inactive, Fe-S cluster-binding proteins. Enzymatically active glutaredoxins harbor both a glutathione-scaffold site for reacting with glutathionylated disu...
Autores principales: | Liedgens, Linda, Zimmermann, Jannik, Wäschenbach, Lucas, Geissel, Fabian, Laporte, Hugo, Gohlke, Holger, Morgan, Bruce, Deponte, Marcel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138851/ https://www.ncbi.nlm.nih.gov/pubmed/32265442 http://dx.doi.org/10.1038/s41467-020-15441-3 |
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