Microvesicle delivery of a lysosomal transport protein to ex vivo rabbit cornea

Therapeutic use of transmembrane proteins is limited because of irreversible denaturation when away from their native lipid membrane. Mutations in lysosomal membrane transport proteins cause many lethal disorders including cystinosis which results from mutations in CTNS, which codes for the lysosoma...

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Detalles Bibliográficos
Autores principales: Thoene, Jess G., DelMonte, Monte A., Mullet, Jodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138922/
https://www.ncbi.nlm.nih.gov/pubmed/32280591
http://dx.doi.org/10.1016/j.ymgmr.2020.100587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138922/
https://www.ncbi.nlm.nih.gov/pubmed/32280591
http://dx.doi.org/10.1016/j.ymgmr.2020.100587

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