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Resveratrol protects mitochondrial quantity by activating SIRT1/PGC‐1α expression during ovarian hypoxia

PURPOSE: Resveratrol is a well‐known potent activator of sirtuin‐1 (SIRT1). We investigated the direct effects of hypoxia and resveratrol on SIRT1/ peroxisome proliferator‐activated receptor‐gamma coactivator 1α (PGC‐1α) pathways, vascular endothelial growth factor (VEGF), hypoxia‐inducible factor (...

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Detalles Bibliográficos
Autores principales: Nishigaki, Akemi, Kido, Takeharu, Kida, Naoko, Kakita‐Kobayashi, Maiko, Tsubokura, Hiroaki, Hisamatsu, Yoji, Okada, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138948/
https://www.ncbi.nlm.nih.gov/pubmed/32273826
http://dx.doi.org/10.1002/rmb2.12323