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Detection of plasma T790M mutation after the first generation EGFR-TKI resistance of non-small cell lung cancer in the real world

BACKGROUND: The epidermal growth factor receptor (EGFR) gene has been identified as the driving gene of non-small cell lung cancer (NSCLC), and EGFR-tyrosine kinase inhibitor (TKI) has shown efficacy, but acquired resistance is inevitable. It has been confirmed that the secondary EGFR Thr790Met (T79...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Wang, Jinwei, Zhang, Guojing, Li, Yuping, Lin, Ling, Yang, Haihua, Zhou, Jingjing, Zhang, Lingna, Lv, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138969/
https://www.ncbi.nlm.nih.gov/pubmed/32274120
http://dx.doi.org/10.21037/jtd.2019.12.122