Loss of ISWI ATPase SMARCA5 (SNF2H) in Acute Myeloid Leukemia Cells Inhibits Proliferation and Chromatid Cohesion

ISWI chromatin remodeling ATPase SMARCA5 (SNF2H) is a well-known factor for its role in regulation of DNA access via nucleosome sliding and assembly. SMARCA5 transcriptionally inhibits the myeloid master regulator PU.1. Upregulation of SMARCA5 was previously observed in CD34+ hematopoietic progenito...

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Detalles Bibliográficos
Autores principales: Zikmund, Tomas, Paszekova, Helena, Kokavec, Juraj, Kerbs, Paul, Thakur, Shefali, Turkova, Tereza, Tauchmanova, Petra, Greif, Philipp A., Stopka, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139293/
https://www.ncbi.nlm.nih.gov/pubmed/32197313
http://dx.doi.org/10.3390/ijms21062073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139293/
https://www.ncbi.nlm.nih.gov/pubmed/32197313
http://dx.doi.org/10.3390/ijms21062073

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