Cargando…
Loss of ISWI ATPase SMARCA5 (SNF2H) in Acute Myeloid Leukemia Cells Inhibits Proliferation and Chromatid Cohesion
ISWI chromatin remodeling ATPase SMARCA5 (SNF2H) is a well-known factor for its role in regulation of DNA access via nucleosome sliding and assembly. SMARCA5 transcriptionally inhibits the myeloid master regulator PU.1. Upregulation of SMARCA5 was previously observed in CD34+ hematopoietic progenito...
Autores principales: | Zikmund, Tomas, Paszekova, Helena, Kokavec, Juraj, Kerbs, Paul, Thakur, Shefali, Turkova, Tereza, Tauchmanova, Petra, Greif, Philipp A., Stopka, Tomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139293/ https://www.ncbi.nlm.nih.gov/pubmed/32197313 http://dx.doi.org/10.3390/ijms21062073 |
Ejemplares similares
-
Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5
por: Dluhosova, Martina, et al.
Publicado: (2014) -
Chromatin Remodeler Smarca5 Is Required for Cancer-Related Processes of Primary Cell Fitness and Immortalization
por: Thakur, Shefali, et al.
Publicado: (2022) -
Correction: Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5
Publicado: (2014) -
Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription
por: Aydin, Özge Z., et al.
Publicado: (2014) -
NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks
por: Vidi, Pierre-Alexandre, et al.
Publicado: (2014)