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PLAG Exerts Anti-Metastatic Effects by Interfering with Neutrophil Elastase/PAR2/EGFR Signaling in A549 Lung Cancer Orthotopic Model

The effectiveness of chemotherapy and radiotherapy to treat lung cancer is limited because of highly metastatic nature. Novel strategies and drugs to attenuate metastatic activity are urgently required. In this study, red fluorescence proteins (RFP)-labeled A549 human lung cancer cells were orthotop...

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Detalles Bibliográficos
Autores principales: Kim, Guen Tae, Hahn, Kyu Woong, Yoon, Sun Young, Sohn, Ki-Young, Kim, Jae Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139301/
https://www.ncbi.nlm.nih.gov/pubmed/32121107
http://dx.doi.org/10.3390/cancers12030560