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Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease

Vascular abnormalities are the most important non-cystic complications in Polycystic Kidney Disease (PKD) and contribute to renal disease progression. Endothelial dysfunction and oxidative stress are evident in patients with ADPKD, preserved renal function, and controlled hypertension. The underlyin...

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Detalles Bibliográficos
Autores principales: Kahveci, Alp S., Barnatan, Tania T., Kahveci, Ali, Adrian, Alexis E., Arroyo, Jennifer, Eirin, Alfonso, Harris, Peter C., Lerman, Amir, Lerman, Lilach O., Torres, Vicente E., Irazabal, Maria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139316/
https://www.ncbi.nlm.nih.gov/pubmed/32183375
http://dx.doi.org/10.3390/ijms21061994