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High Prevalence of Alterations in DNA Mismatch Repair Genes of Lynch Syndrome in Pediatric Patients with Adrenocortical Tumors Carrying a Germline Mutation on TP53

Adrenocortical cancer is a rare malignant neoplasm associated with a dismal prognosis. Identification of the molecular pathways involved in adrenal tumorigenesis is essential for a better understanding of the disease mechanism and improvement of its treatment. The aim of this study is to define the...

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Detalles Bibliográficos
Autores principales: Brondani, Vania Balderrama, Montenegro, Luciana, Lacombe, Amanda Meneses Ferreira, Magalhães, Breno Marchiori, Nishi, Mirian Yumie, Funari, Mariana Ferreira de Assis, Narcizo, Amanda de Moraes, Cardoso, Lais Cavalca, Siqueira, Sheila Aparecida Coelho, Zerbini, Maria Claudia Nogueira, Denes, Francisco Tibor, Latronico, Ana Claudia, Mendonca, Berenice Bilharinho, Almeida, Madson Queiroz, Lerario, Antonio Marcondes, Soares, Ibere Cauduro, Fragoso, Maria Candida Barisson Villares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139318/
https://www.ncbi.nlm.nih.gov/pubmed/32156018
http://dx.doi.org/10.3390/cancers12030621