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IQGAP2 Inhibits Migration and Invasion of Gastric Cancer Cells via Elevating SHIP2 Phosphatase Activity

Previous studies have shown reduced expression of Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) and its tumor-suppressive role in gastric cancer (GC). However, the precise role of SHIP2 in the migration and invasion of GC cells remains unclear. Here, an IQ motif containing the GTPase-ac...

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Detalles Bibliográficos
Autores principales: Xu, Liang, Shao, Yuling, Ren, Lin, Liu, Xiansheng, Li, Yunyun, Xu, Jiegou, Ye, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139352/
https://www.ncbi.nlm.nih.gov/pubmed/32183047
http://dx.doi.org/10.3390/ijms21061968