Weaning Mice and Adult Mice Exhibit Differential Carbon Tetrachloride-Induced Acute Hepatotoxicity

Age is a risk factor for drug-induced liver injury (DILI). However, there is a limited understanding of pediatric DILI. Here, 2-week-old weaning and 8-week-old adult male ICR mice were intraperitoneally injected with CCl(4) (0.1 mmol/kg equal to 15.4 mg/kg) to comparatively evaluate the time-depende...

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Detalles Bibliográficos
Autores principales: Jeong, Tae Bin, Kwon, Doyoung, Son, Seung Won, Kim, Sou Hyun, Lee, Yun-Hee, Seo, Min-Soo, Kim, Kil Soo, Jung, Young-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139353/
https://www.ncbi.nlm.nih.gov/pubmed/32121508
http://dx.doi.org/10.3390/antiox9030201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139353/
https://www.ncbi.nlm.nih.gov/pubmed/32121508
http://dx.doi.org/10.3390/antiox9030201

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