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Huntingtin Lowering Strategies

Trials using antisense oligonucleotide technology to lower Huntingtin levels in Huntington’s disease (HD) are currently ongoing. This progress, taking place only 27 years after the identification of the Huntingtin gene (HTT) in 1993 reflects the enormous development in genetic engineering in the las...

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Detalles Bibliográficos
Autores principales: Marxreiter, Franz, Stemick, Judith, Kohl, Zacharias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139361/
https://www.ncbi.nlm.nih.gov/pubmed/32245050
http://dx.doi.org/10.3390/ijms21062146