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Pioglitazone and Deoxyribonucleoside Combination Treatment Increases Mitochondrial Respiratory Capacity in m.3243A>G MELAS Cybrid Cells

The lack of effective treatments for mitochondrial disease has seen the development of new approaches, including those that aim to stimulate mitochondrial biogenesis to boost ATP generation above a critical disease threshold. Here, we examine the effects of the peroxisome proliferator-activated rece...

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Detalles Bibliográficos
Autores principales: Burgin, Harrison J., Lopez Sanchez, M. Isabel G., Smith, Craig M., Trounce, Ian A., McKenzie, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139379/
https://www.ncbi.nlm.nih.gov/pubmed/32244971
http://dx.doi.org/10.3390/ijms21062139