Calcium-Dependent Calpain Activation-Mediated Mitochondrial Dysfunction and Oxidative Stress Are Required for Cytotoxicity of Epinecidin-1 in Human Synovial Sarcoma SW982 Cells

Synovial sarcoma is a rare but highly malignant and metastatic disease. Despite its relative sensitivity to chemotherapies, the high recurrence and low 5-year survival rate for this disease suggest that new effective therapeutic agents are urgently needed. Marine antimicrobial peptide epinecidin-1 (...

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Detalles Bibliográficos
Autores principales: Su, Bor-Chyuan, Li, Chao-Chin, Horng, Jiun-Lin, Chen, Jyh-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139453/
https://www.ncbi.nlm.nih.gov/pubmed/32204400
http://dx.doi.org/10.3390/ijms21062109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139453/
https://www.ncbi.nlm.nih.gov/pubmed/32204400
http://dx.doi.org/10.3390/ijms21062109

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