Recovery of Adrenal Insufficiency Is Frequent After Adjuvant Mitotane Therapy in Patients with Adrenocortical Carcinoma

Mitotane is a steroidogenesis inhibitor and adrenolytic drug used for treatment of adrenocortical cancer (ACC). Mitotane therapy causes adrenal insufficiency requiring glucocorticoid replacement in all patients. However, it is unclear whether chronic therapy with mitotane induces complete destructio...

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Detalles Bibliográficos
Autores principales: Poirier, Jonathan, Gagnon, Nadia, Terzolo, Massimo, Puglisi, Soraya, Ghorayeb, Nada El, Calabrese, Anna, Lacroix, André, Bourdeau, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139486/
https://www.ncbi.nlm.nih.gov/pubmed/32164326
http://dx.doi.org/10.3390/cancers12030639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139486/
https://www.ncbi.nlm.nih.gov/pubmed/32164326
http://dx.doi.org/10.3390/cancers12030639

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