Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α(-/-) Mouse Model

Increased oxidative stress and mitochondrial damage are observed in protein aggregation diseases, such as age-related macular degeneration (AMD). We have recently reported elevated levels of oxidative stress markers, damaged mitochondria, accumulating lysosomal lipofuscin and extracellular drusen-li...

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Detalles Bibliográficos
Autores principales: Sridevi Gurubaran, Iswariyaraja, Viiri, Johanna, Koskela, Ali, Hyttinen, Juha M.T., Paterno, Jussi J., Kis, Gréta, Antal, Miklós, Urtti, Arto, Kauppinen, Anu, Felszeghy, Szabolcs, Kaarniranta, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139489/
https://www.ncbi.nlm.nih.gov/pubmed/32183173
http://dx.doi.org/10.3390/ijms21061976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139489/
https://www.ncbi.nlm.nih.gov/pubmed/32183173
http://dx.doi.org/10.3390/ijms21061976

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