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New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

In this paper, a novel series of imidazole-based heme oxygenase-1 (HO-1) inhibitors is reported. These compounds were obtained by modifications of previously described high potent and selective arylethanolimidazoles. In particular, simplification of the central linker and repositioning of the hydrop...

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Detalles Bibliográficos
Autores principales: Ciaffaglione, Valeria, Intagliata, Sebastiano, Pittalà, Valeria, Marrazzo, Agostino, Sorrenti, Valeria, Vanella, Luca, Rescifina, Antonio, Floresta, Giuseppe, Sultan, Ameera, Greish, Khaled, Salerno, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139504/
https://www.ncbi.nlm.nih.gov/pubmed/32168943
http://dx.doi.org/10.3390/ijms21061923