Testing of the Survivin Suppressant YM155 in a Large Panel of Drug-Resistant Neuroblastoma Cell Lines

The survivin suppressant YM155 is a drug candidate for neuroblastoma. Here, we tested YM155 in 101 neuroblastoma cell lines (19 parental cell lines, 82 drug-adapted sublines). Seventy seven (77) cell lines displayed YM155 IC(50)s in the range of clinical YM155 concentrations. ABCB1 was an important...

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Detalles Bibliográficos
Autores principales: Michaelis, Martin, Voges, Yvonne, Rothweiler, Florian, Weipert, Fabian, Zia-Ahmad, Amara, Cinatl, Jaroslav, von Deimling, Andreas, Westermann, Frank, Rödel, Franz, Wass, Mark N., Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139505/
https://www.ncbi.nlm.nih.gov/pubmed/32131402
http://dx.doi.org/10.3390/cancers12030577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139505/
https://www.ncbi.nlm.nih.gov/pubmed/32131402
http://dx.doi.org/10.3390/cancers12030577

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