Potential Applications of NRF2 Modulators in Cancer Therapy

The nuclear factor erythroid 2-related factor 2 (NRF2)–Kelch-like ECH-associated protein 1 (KEAP1) regulatory pathway plays an essential role in protecting cells and tissues from oxidative, electrophilic, and xenobiotic stress. By controlling the transactivation of over 500 cytoprotective genes, the...

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Detalles Bibliográficos
Autores principales: Panieri, Emiliano, Buha, Aleksandra, Telkoparan-Akillilar, Pelin, Cevik, Dilek, Kouretas, Demetrios, Veskoukis, Aristidis, Skaperda, Zoi, Tsatsakis, Aristidis, Wallace, David, Suzen, Sibel, Saso, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139512/
https://www.ncbi.nlm.nih.gov/pubmed/32106613
http://dx.doi.org/10.3390/antiox9030193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139512/
https://www.ncbi.nlm.nih.gov/pubmed/32106613
http://dx.doi.org/10.3390/antiox9030193

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