Reduced SKP1 Expression Induces Chromosome Instability through Aberrant Cyclin E1 Protein Turnover

Chromosome instability (CIN), or progressive changes in chromosome numbers, is an enabling feature of many cancers; however, the mechanisms giving rise to CIN remain poorly understood. To expand our mechanistic understanding of the molecular determinants of CIN in humans, we employed a cross-species...

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Detalles Bibliográficos
Autores principales: Thompson, Laura L., Baergen, Allison K., Lichtensztejn, Zelda, McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139525/
https://www.ncbi.nlm.nih.gov/pubmed/32106628
http://dx.doi.org/10.3390/cancers12030531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139525/
https://www.ncbi.nlm.nih.gov/pubmed/32106628
http://dx.doi.org/10.3390/cancers12030531

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