Sexually Dimorphic Behavioral Profile in a Transgenic Model Enabling Targeted Recombination in Active Neurons in Response to Ketamine and (2R,6R)-Hydroxynorketamine Administration

Background: Rapid-acting antidepressants ketamine and (2R,6R)-hydroxynorketamine ((2R,6R)-HNK) have overcome some of the major limitations of classical antidepressants. However, little is known about sex-specific differences in the behavioral and molecular effects of ketamine and (2R,6R)-HNK in rode...

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Detalles Bibliográficos
Autores principales: Herzog, David P., Mellema, Ratnadevi M., Remmers, Floortje, Lutz, Beat, Müller, Marianne B., Treccani, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139539/
https://www.ncbi.nlm.nih.gov/pubmed/32244978
http://dx.doi.org/10.3390/ijms21062142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139539/
https://www.ncbi.nlm.nih.gov/pubmed/32244978
http://dx.doi.org/10.3390/ijms21062142

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