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Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain

Oligomerization and/or aggregation of α-synuclein (α-Syn) triggers α-synucleinopathies such as Parkinson’s disease and dementia with Lewy bodies. It is known that α-Syn can spread in the brain like prions; however, the mechanism remains unclear. We demonstrated that fatty acid binding protein 3 (FAB...

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Detalles Bibliográficos
Autores principales: Yabuki, Yasushi, Matsuo, Kazuya, Kawahata, Ichiro, Fukui, Naoya, Mizobata, Tomohiro, Kawata, Yasushi, Owada, Yuji, Shioda, Norifumi, Fukunaga, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139546/
https://www.ncbi.nlm.nih.gov/pubmed/32210174
http://dx.doi.org/10.3390/ijms21062230