Absence of Nuclear p16 Is a Diagnostic and Independent Prognostic Biomarker in Squamous Cell Carcinoma of the Cervix

The tumor-suppressor protein p16 is paradoxically overexpressed in cervical cancer (CC). Despite its potential as a biomarker, its clinical value and the reasons for its failure in tumor suppression remain unclear. Our purpose was to determine p16 clinical and biological significance in CC. p16 expr...

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Detalles Bibliográficos
Autores principales: Mendaza, Saioa, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Zudaire, Tamara, Guarch, Rosa, Guerrero-Setas, David, Vidal, August, Santos-Salas, José, Matias-Guiu, Xavier, Ausín, Karina, Díaz de Cerio, María José, Martín-Sánchez, Esperanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139571/
https://www.ncbi.nlm.nih.gov/pubmed/32204550
http://dx.doi.org/10.3390/ijms21062125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139571/
https://www.ncbi.nlm.nih.gov/pubmed/32204550
http://dx.doi.org/10.3390/ijms21062125

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