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Macrophage-Secreted Lipocalin-2 Promotes Regeneration of Injured Primary Murine Renal Tubular Epithelial Cells

Lipocalin-2 (Lcn-2) is rapidly upregulated in macrophages after renal tubular injury and acts as renoprotective and pro-regenerative agent. Lcn-2 possesses the ability to bind and transport iron with high affinity. Therefore, the present study focuses on the decisive role of the Lcn-2 iron-load for...

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Detalles Bibliográficos
Autores principales: Urbschat, Anja, Thiemens, Anne-Kathrin, Mertens, Christina, Rehwald, Claudia, Meier, Julia K., Baer, Patrick C., Jung, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139578/
https://www.ncbi.nlm.nih.gov/pubmed/32188161
http://dx.doi.org/10.3390/ijms21062038