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Injection Molded Capsules for Colon Delivery Combining Time-Controlled and Enzyme-Triggered Approaches

A new type of colon targeting system is presented, combining time-controlled and enzyme-triggered approaches. Empty capsule shells were prepared by injection molding of blends of a high-amylose starch and hydroxypropyl methylcellulose (HPMC) of different chain lengths. The dissolution/erosion of the...

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Detalles Bibliográficos
Autores principales: Casati, Federica, Melocchi, Alice, Moutaharrik, Saliha, Uboldi, Marco, Foppoli, Anastasia, Maroni, Alessandra, Zema, Lucia, Neut, Christel, Siepmann, Florence, Siepmann, Juergen, Gazzaniga, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139580/
https://www.ncbi.nlm.nih.gov/pubmed/32168895
http://dx.doi.org/10.3390/ijms21061917