SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation

The MAP kinase ERK5 contains an N-terminal kinase domain and a unique C-terminal tail including a nuclear localization signal and a transcriptional activation domain. ERK5 is activated in response to growth factors and stresses and regulates transcription at the nucleus by either phosphorylation or...

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Detalles Bibliográficos
Autores principales: Erazo, Tatiana, Espinosa-Gil, Sergio, Diéguez-Martínez, Nora, Gómez, Néstor, Lizcano, Jose M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139592/
https://www.ncbi.nlm.nih.gov/pubmed/32209980
http://dx.doi.org/10.3390/ijms21062203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139592/
https://www.ncbi.nlm.nih.gov/pubmed/32209980
http://dx.doi.org/10.3390/ijms21062203

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